Read Consolidative therapy with stem cell transplantation improves survival of patients with mantle cell lymphoma after any induction regimen - Reddy N.; Greer J.P.; Goodman S.; Kassim A.; Morgan D.S.; All authors file in PDF
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The study, “ long-term outcomes after autologous stem cell transplantation for multiple myeloma,” was published in the journal blood advances. An important component of multiple myeloma treatment is autologous stem cell transplantation (asct), which consists on using a patient’s own healthy blood stem cells to replace diseased or damaged bone marrow.
We retrospectively identified patients who had light chain amyloidosis and underwent autologous stem cell transplant at the mayo clinic. Consolidation was defined as any treatment given after the day 100 evaluation post‐transplant to maintain or deepen the response. We identified 471 patients, of whom 72 (15%) received consolidation.
Consolidation therapy with autologous stem cell transplantation in plasma cell leukemia after vad, high-dose cyclophosphamide and edap courses: a report of three cases and a review of the literature.
The rationale for consolidation treatment in pcnsl is to eliminate residual lymphoma cells and to decrease the risk for relapse. This can be achieved by agents crossing the blood brain barrier either applied at conventional doses or at high doses requiring autologous stem cell support.
Autologous stem-cell transplantation as consolidation therapy for diffuse large b-cell lymphoma patients with overexpression of bcl-2 protein. Results of the groupe d'etude des lymphomes de l'adulte (gela) trial lnh98-b2.
Editor's note: consolidation therapy means using the same therapy (typically) that was used during induction therapy. It is usually a combination of myeloma therapies used at the same dose and frequency as the induction therapy and is used for 2-12 months following a stem cell transplant.
In some treatment processes, such as with the treatment of acute leukemia, consolidation chemotherapy is a follow-up to the induction therapy that is administered in an attempt to kill the cancer cells. If the induction therapy proves to be successful and the patient responds favorably, then consolidation is initiated in the hopes of helping.
Mar 6, 2021 therapy after autologous stem cell transplantation in children or refractory hodgkin lymphoma treated with consolidative bren- tuximab.
There is no consensus about intensive chemotherapy as a consolidation and/or stem cell transplantation (sct) after first remission (cr1). Allogeneic stem cell transplantation (allo-sct) for acute leukemias has been increased due to the developments of allo-sct techniques.
Consolidation therapy with high-dose melphalan plus stem-cell transplantation, as compared with mpr, significantly prolonged progression-free and overall survival among patients with multiple.
For some children in high-risk groups, a stem cell transplant might be an option at this time once the leukemia is in remission. If the leukemia remains in remission after induction and consolidation, maintenance therapy can begin.
In a recent randomized, placebo‐controlled trial, consolidation treatment with brentuximab vedotin (bv) decreased the risk of hodgkin lymphoma (hl) progression after autologous stem cell transplantation (asct). However, the impact of bv consolidation on overall survival, quality of life, and health care costs remain unclear.
Global oncology news join specialists as they discuss the lung cancer landscape live broadcast: a new treatment option for some patients with triple-class refractory multiple myeloma neoadjuvant.
Brentuximab vedotin as consolidation therapy after autologous stem-cell transplantation in patients with hodgkin’s lymphoma at risk of relapse or progression (aethera): a randomised, double-blind, placebo-controlled, phase 3 trial.
Purita is the pioneer of orthopedic stem cell and platelet rich plasma (prp) treatments.
Autologous stem cell transplantation versus chemotherapy for adult patients with acute myeloid leukemia in first remission: the bgmt group experience.
Acute myeloid leukemia consolidation therapy involves multiple courses of chemotherapy or high-dose chemotherapy with stem cell transplantation.
Consolidative high-dose therapy and autologous stem cell transplantation (hdt/asct) should not be offered to patients with follicular lymphoma who are in their first remission after having initially received treatment with rituxan (rituximab) plus the chemotherapies cyclophosphamide, doxorubicin and vincristine in addition to the steroid prednisone (r-chop), according to the authors of a recent study published in blood advances.
Mar 16, 2020 but as new medicines became available, they were incorporated into induction, consolidation, and maintenance treatments as standard.
Sep 4, 2013 what consolidation therapy typically means is that after successful transplant after stem cell mobilization for rvd consolidation and then.
Jan 29, 2015 retinoic acid post consolidation therapy for high‐risk neuroblastoma patients treated with autologous hematopoietic stem cell transplantation.
It can take really up to three months to really see the full benefit of transplant. And also, because we want to start maintenance therapy or this concept of consolidation therapy. So, we usually repeat the myeloma tests around eight weeks after.
Jan 22, 2020 the treatment of aml is divided into two phases: remission induction and consolidation/maintenance.
Second phase — consolidation chemotherapy, which may include stem cell transplantation; third phase — in some cases, blood or marrow transplant (bmt).
Consolidation therapy with brentuximab vedotin after allogeneic stem cell transplantation for relapsed or refractory hodgkin lymphoma the safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
3331 high-dose chemotherapy (hdc) with autologous stem-cell transplant ( asct) with consolidative radiation therapy (rt) for relapsed or refractory.
In the united states, approximately 55% to 60% of patients with relapsed/ refractory hodgkin lymphoma are cured with salvage therapy followed by a stem cell.
Consolidation treatment is also called post-remission therapy. The goal of consolidation treatment for acute myelogenous leukemia (aml) is to prevent leukemia cells from coming back. It is done to maintain complete remission and prevent relapse.
What do i need to know about consolidation therapy and stem cell transplants? after induction therapy for aml, there is a second phase of therapy called “consolidation,” which is intended to rid the body of any remaining cancer cells. There are many different consolidation therapy treatment options, from chemotherapy to stem cell transplant.
The non-hodgkin lymphomas (nhls) are a heterogeneous group of diseases with variable clinical outcomes. Autologous hematopoietic stem-cell transplantation (asct) as frontline, consolidative therapy.
Children with low-risk medulloblastoma will all receive a single cycle of consolidation therapy. Patients will then receive an infusion of their stored stem cells.
May 25, 2020 10539background: treatment of high-risk nb within the major stem-cell transplantation in high-risk neuroblastoma consolidated by anti-gd2.
Consolidation therapy can be accomplished with multiple courses of chemotherapy or high-dose chemotherapy with autologous or allogeneic stem cell.
Consolidative therapy with stem cell transplantation improves survival of patients with mantle cell lymphoma after any induction regimen january 2012 experimental hematology 40(5):359-66.
Interpretation consolidation therapy with thalidomide and prednisolone after autologous stem-cell transplantaion is an acceptable therapeutic approach when alternative drugs are not available.
More than half of aml patients achieved complete remission after standard induction therapy but 60–70% of patients will.
Apr 5, 2017 lymphoma treatment, kate arnold received a stem cell transplant. Her local oncologist, she began consolidation therapy to shrink the tumor.
Consolidation therapy is a treatment that is given after cancer has disappeared following the initial therapy. Consolidation therapy is used to kill any cancer cells that may be left in the body. It may include radiation therapy, a stem cell transplant, or treatment with drugs that kill cancer cells.
Early consolidation with brentuximab vedotin after autologous stem-cell transplantation improved progression-free survival in patients with hodgkin's lymphoma with risk factors for relapse or progression after transplantation. This treatment provides an important therapeutic option for patients undergoing autologous stem-cell transplantation.
Nov 1, 2020 our aim was to assess clinical outcomes in pts undergoing salvage autologous stem cell transplant (asct) for relapsed or refractory hodgkin.
A stem cell transplant is a common treatment for multiple myeloma. If you’re able to have one, you’ll get induction therapy followed by a high dose of a chemotherapy drug to kill as many.
Autologous haematopoietic stem-cell transplantation versus bortezomib–melphalan–prednisone, with or without bortezomib–lenalidomide–dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (emn02/ho95): a multicentre, randomised, open-label, phase 3 study.
Consolidation therapy consolidation therapy for multiple myeloma is a short course of chemotherapy, given after a stem cell transplant. Consolidation therapy helps make the previous chemotherapy treatment and stem cell transplant work better. Consolidation therapy also helps to keep the multiple myeloma in remission for a longer period of time.
We retrospectively reviewed the treatment modalities and prognosis of 56 relapsed nktcl patients. Chemotherapy was the initial salvage treatment, followed by radiotherapy (rt) or autologous hematopoietic stem cell transplantation (ahsct) as consolidative therapy, depending on the status of remission and the pattern of relapse.
May 25, 2020 consolidation treatment after autologous stem cells transplantation in patients hodgkin lymphoma, consolidation therapy, post-autologous.
Nov 13, 2019 introduction: high-dose chemotherapy followed by autologous stem-cell transplantation (auto-hct) is standard of care for patients with.
Following successful induction therapy, patients with high-risk all are given one cycle of intensive consolidation chemotherapy. When the blood counts begin to return to normal after consolidation therapy, stem cells are collected from the blood using a technique called apheresis.
Mar 1, 2007 the consolidation therapy consisted of non-infusional or infusional idarubicin, etposide and cytarabine (mini-ice).
Background: high-dose therapy followed by autologous stem-cell transplantation is standard of care for patients with relapsed or primary refractory hodgkin's lymphoma. Roughly 50% of patients might be cured after autologous stem-cell transplantation; however, most patients with unfavourable risk factors progress after transplantation.
Myeloablative consolidation therapy and tandem autologous stem cell rescue in patients with high-risk neuroblastoma the safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
Treatment begins as soon as possible and varies by age, general condition and cytogenetics results. Typical therapy includes three phases: first phase — induction chemotherapy; second phase — consolidation chemotherapy, which may include stem cell transplantation.
For some patients, bone marrow/stem cell transplantation (see below) is recommended as part of post-remission therapy.
Sep 3, 2020 without post-remission therapy (consolidation), the leukemia is likely to stem cell transplants have been found to reduce the risk of leukemia.
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